Category: Uncategorized
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Clarivein® might have a role in the treatment of truncal pelvic vein reflux, but not in the treatment of pelvic varicosities – results from an ovine model.
Aims: Pelvic vein embolisation is the recognised treatment for symptomatic pelvic vein reflux. There is a requirement to ablate incompetent pelvic veins without using an implantable device. The aim of this study was to assess the use of the Clarivein® device as a potential method of ablating incompetent pelvic veins. Methods: An ovine model was…
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One-year results of treatment of incompetent truncal veins and incompetent perforators using 8 and 4 second pulses of High Intensity Focused Ultrasound (HIFU)
Introduction: High Intensity Focused Ultrasound (HIFU) is a new extra-corporeal, non-invasive thermoablative technique to treat superficial venous incompetence in leg veins, which left untreated can cause symptomatic varicose veins and venous leg ulcers. To date, there is limited data surrounding the treatment outcomes of HIFU. This study aims to show the 1-year results of using…
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Pelvic Congestion Syndrome affects nulliparous and post-menopausal women, and the treatment of internal iliac vein reflux is critical: A retrospective cohort study looking at treatment outcomes following Pelvic Vein Embolisation.
Objective To identify the effects of patient risk factors and pelvic venous reflux (PVR) patterns on treatment outcomes of Pelvic Vein Embolisation (PVE) for Pelvic Congestion Syndrome (PCS). Methods We performed a retrospective cohort review assessing population, intervention, comparison and outcomes (PICO) for women undergoing PVE for PCS January 2017–January 2021. We identified 190 patients…
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Veins undergoing endovenous thermal ablation have little or no blood intra-luminally casting doubt on the results of many ex-vivo vein ablation studies.
Objectives: Endovenous thermal ablation (EVTA) is the first-line treatment for varicose veins. Many in-vitro models have been made to study the effects of EVTA on the vein wall. Models using explanted human great saphenous vein (GSV) use anticoagulated blood passed into the vein during treatment, either static or being pumped to simulate “physiological flow”. The…
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Syncope (fainting on standing from squatting) due to massive venous reflux into lower limb varicose veins.
A 42-year-old man presented with very large lower limb varicose veins bilaterally and an 8-month history of fainting when standing up from a squatting position. He had been investigated for syncope by a cardiologist with no abnormality found on ECG, Echocardiogram, 24-hour ECG or 48-hour blood pressure monitoring. Venous duplex ultrasonography showed bilaterally Great Saphenous…
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Comparison of detergent and osmotic sclerotherapy agent action on ex-vivo human vein – a histological and immunocytochemical analysis
Background: Sclerotherapy is used widely for the treatment of varicose veins. Little has been written on the mechanism of action of detergent sclerosants on the vein wall, and very little on osmotic sclerosants. We compared the damage profile inflicted by a detergent sclerosant (3% Sodium Tetradecyl Sulphate (3% STS)) to that of an osmotic sclerosant…
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Vein wall thickness (VWT) and catheter size are more important than vein diameter in optimising endovenous thermal ablation (EVTA) – results of a mathematical model of how VWT changes when veins constrict under tumescence.
Background: Catheter-based endovenous thermal ablation (EVTA) under tumescent anaesthesia is the standard treatment for truncal venous reflux. Doctors often use vein diameter alone to select treatment settings and protocols. Adequate venous ablation requires thermal energy to penetrate the vein wall deeply and probably transmurally. Hence the thicker the vein wall when constricted during treatment, the…
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Participant Reported Improvement in Cellulite by Vari-pad Apparel and Objective Measurements – a “First Use” Pilot Study.
Background: Cellulite affects 80-90% of post-pubertal females and, although cosmetic, has proven adverse psychological effects. A new compression garment with patented “vari-pad” technology has been developed, aiming to stimulate lymphatic return from the buttocks and thighs. The primary aim of this small pilot study was to assess participant satisfaction after using this garment in the…
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Mathematics
Mathematics is a discipline that deals with the study of numbers, quantities, shapes, patterns, structures, and their relationships. It provides a framework for logical reasoning and precise analysis, allowing us to understand and describe the patterns and structures that exist in the world around us. Mathematics is considered a fundamental science and plays a vital…